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S6180549

≥80%(HPLC),solid , 76343-94-7

Synonym(s):
LAT-B;Latrunculin B, Latrunculia magnifica - CAS 76343-94-7 - Calbiochem

CAS NO.:76343-94-7

Empirical Formula: C20H29NO5S

Molecular Weight: 395.51

MDL number: MFCD00270879

Pack Size Price Stock Quantity
1mg RMB2800.88 In Stock
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Update time: 2022-07-08

PRODUCT Properties

alpha  D24 +112° (c = 0.48 in chloroform)
storage temp.  -20°C
solubility  DMSO: soluble
form  solid
color  light yellow
optical activity +120.123 (CHCl3)
Stability: Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.

Description and Uses

Latrunculin B (76343-94-7) inhibits actin polymerization and disrupts microfilament organization.1 Significantly more potent than cytochalasins in the disruption of microfilament mediated processes2, causes shortening and thickening of stress fibers. Active in cell culture.3,4?Effective doses for latrunculin B vary depending upon cell type but are frequently in the low micromolar range. Note: Latrunculin B is slowly inactivated by fetal bovine serum.

Latrunculin B is an actin polymerization inhibitor.

Safety

WGK Germany  3

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