S3847651
≥98%(HPLC) , 299-75-2
Synonym(s):
(2S,3S)-Butanetetraol 1,4-dimesylate;(2S,3S)-Threitol 1,4-bismethanesulfonate;L-Threitol 1,4-bis(methanesulfonate);Threosulphan;Treosulphan
| Pack Size | Price | Stock | Quantity |
| 5MG | RMB1033.46 | In Stock |
|
| 25MG | RMB4165.50 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | 76-78 °C |
| Boiling point: | 359.3°C (rough estimate) |
| Density | 1.305 (estimate) |
| refractive index | 1.5630 (estimate) |
| storage temp. | Store at -20°C |
| solubility | Acetone (Slightly), DMSO (Slightly), Methanol (Slightly), Water (Slightly) |
| form | Solid |
| pka | 12.36±0.20(Predicted) |
| color | Off-White to Pale Beige |
| optical activity | [α]/D -4.9 to -5.9°, c =1 in acetone |
| Water Solubility | H2O: 5mg/mL, clear |
| CAS DataBase Reference | 299-75-2 |
| IARC | 1 (Vol. 26, Sup 7, 100A) 2012 |
| EPA Substance Registry System | Treosulfan (299-75-2) |
Description and Uses
Treosulfan is used as myeloablative agent in conditioning regimen prior to allogeneic hematopoietic stem cell transplantation (HSCT)??. It can also be an effective agent for conditioning children with inborn errors of immunity (IEI).
Safety
| Symbol(GHS) |  GHS08 |
| Signal word | Danger |
| Hazard statements | H340-H350-H361f |
| Precautionary statements | P201-P202-P280-P308+P313-P405-P501 |
| RIDADR | 2811 |
| HazardClass | 6.1(b) |
| PackingGroup | III |
| Hazardous Substances Data | 299-75-2(Hazardous Substances Data) |
| Toxicity | LDLo intravenous in dog: 222mg/kg |
