Naltrexone , 98% , 16590-41-3

Synonym(s):
(5α)-17-(Cyclopropylmethyl)-4,5-epoxy-3,14-dihydroxymorphinan-6-one

CAS NO.：16590-41-3

Empirical Formula: C20H23NO4

Molecular Weight: 341.4

MDL number: MFCD00242996

EINECS: 240-649-9

PRODUCT Properties

• Melting point: 168-170°
• Boiling point: 477.03°C (rough estimate)
• Density: 1.2064 (rough estimate)
• refractive index: 1.5614 (estimate)
• Flash point: 9℃
• storage temp.: 2-8°C
• solubility: Chloroform (Slightly), Methanol (Slightly)
• pka: pKa 8.38/8.13(H2O,t =20/37,I<0.01) (Uncertain)
• form: Solid
• color: White to Light Beige
• EPA Substance Registry System: Naltrexone (16590-41-3)

Description and Uses

This drug does not have agonistic properties. It is similar to naloxone in terms of pharmacological characteristics; however, it differs in two important ways—long-lasting action and that its metabolite 6-β-naltrexol is also a strong antagonist. Naltrexone is potentially hepatotoxic. Naltrexone is used for blocking pharmacological effects of opioids upon their overdose.

anthelmintic, teniacide

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H302-H336
• Precautionary statements: P261-P264-P270-P271-P301+P312-P304+P340+P312
• Hazard Codes: F,T
• Risk Statements: 11-23/24/25-39/23/24/25
• Safety Statements: 16-36/37-45
• RIDADR: UN1230 - class 3 - PG 2 - Methanol, solution
• WGK Germany: 1
• HS Code: 2939190000
• Hazardous Substances Data: 16590-41-3(Hazardous Substances Data)
• Toxicity: LD50 in mice (mg/kg): 586 s.c. (Maickel)