ProstaglandinE2p-benzamidophenylester(PGE2p-benzamidophenylester) , 98% , 57790-53-1

CAS NO.：57790-53-1

Empirical Formula: C33H41NO6

Molecular Weight: 547.68

MDL number: MFCD02259328

PRODUCT Properties

• solubility: DMF: 65 mg/ml; DMSO: 28 mg/ml; Ethanol: 6 mg/ml; PBS pH 7.2: <125 μg/ml
• form: A crystalline solid

Description and Uses

PGE₂ p-benzamidophenyl ester is a crystalline derivative of PGE₂. PGE₂ is one of the primary COX products of arachidonic acid and one of the most widely investigated prostaglandins. Its activity influences inflammation, fertility and parturition, gastric mucosal integrity, and immune modulation.^1,2,3,4 The effects of PGE₂ are transduced by at least four distinct receptors designated EP₁, EP₂, EP₃, and EP₄.⁵ Affinity constants (K_d) of PGE₂ for these receptors range from 1-10 nM depending on the receptor subtype and tissue.

Safety

• Symbol(GHS): GHS07,GHS08
• Signal word: Danger
• Hazard statements: H302-H360
• Precautionary statements: P201-P202-P264-P270-P280-P301+P312-P330-P308+P313-P405-P501