ProstaglandinE2p-acetamidophenylester(PGE2p-acetamidophenylester) , 98% , 57790-52-0

CAS NO.：57790-52-0

Empirical Formula: C28H39NO6

Molecular Weight: 485.61

MDL number: MFCD02259327

PRODUCT Properties

• solubility: DMF: >38 mg/ml; DMSO: >35 mg/ml; Ethanol: >40 mg/ml; Ethanol:PBS (1:1): <50 μg/ml
• form: A crystalline solid

Description and Uses

PGE₂ p-acetamidophenyl ester is a crystalline derivative of PGE₂. PGE₂ is one of the primary COX products of arachidonic acid and one of the most widely investigated prostaglandins. Its activity influences inflammation, fertility and parturition, gastric mucosal integrity, and immune modulation.^1,2,3,4 The effects of PGE₂ are transduced by at least four distinct receptors designated EP₁, EP₂, EP₃, and EP₄.⁵ Affinity constants (K_d) of PGE₂ for these receptors range from 1-10 nM depending on the receptor subtype and tissue.

Safety

• Symbol(GHS): GHS07,GHS08
• Signal word: Danger
• Hazard statements: H302-H360
• Precautionary statements: P201-P202-P264-P270-P280-P301+P312-P330-P308+P313-P405-P501