Amrubicin(AMR) , ≥98% , 110267-81-7
| Pack Size | Price | Stock | Quantity |
| 5mg | RMB4675.20 | In Stock |
|
| others | Enquire |
PRODUCT Properties
| Melting point: | 172-1740C |
| alpha | D20 +119° (c = 0.02 in CHCl3) |
| Boiling point: | 717.8±60.0 °C(Predicted) |
| Density | 1.60±0.1 g/cm3(Predicted) |
| storage temp. | Store at -20°C |
| solubility | >16.45mg/mL in DMSO |
| form | Powder |
| pka | 7.83±0.60(Predicted) |
| color | Pink to red |
Description and Uses
Amrubicin is an active agent for the treatment of small-cell lung cancer (SCLC). It is a type of anthracycline analog. Anthracycline derivatives such as doxorubicin (DXR), daunorubicin (DNR) and epirubicin have been widely used for a variety of carcinomas in the clinical context. Amrubicin is structurally distinguishable from other anthracyclines by the amino group at the 9-position and its unique sugar moiety. In April 2002, Amrubicin was approved in Japan for the treatment of non-small cell lung cancer and small cell lung cancer.
Synthetic anthracycline antibiotic; inhibits DNA topoisomerase II. Antineoplastic. Amrubicin is used to treat small-cell lung cancer (SCLC).
