Dexrazoxane , 10mMinDMSO , 24584-09-6

Synonym(s):
(+)-(S)-4,4′-Propylenedi-2,6-piperazinedione;(S)-(+)-1,2-Bis(3,5-dioxopiperazin-1-yl)propane;Cardioxane;Zinecard

CAS NO.：24584-09-6

Empirical Formula: C11H16N4O4

Molecular Weight: 268.27

MDL number: MFCD00866449

Pack Size	Price	Stock	Quantity
1ml	RMB159.20	In Stock
others			Enquire

Update time: 2022-07-08

PRODUCT Properties

Melting point:	194-196°C
alpha	D +11.35° (c = 5 in DMF)
Boiling point:	531.5±50.0 °C(Predicted)
Density	1.333±0.06 g/cm3(Predicted)
storage temp.	2-8°C
solubility	DMSO: >20mg/mL
form	powder
pka	2.1(at 25℃)
color	white to off-white
Merck	14,8123
InChIKey	BMKDZUISNHGIBY-ZETCQYMHSA-N

Description and Uses

Dexrazoxane is the dextro-isomer of razoxane approved as a protectant against the cardiotoxicity of doxorubicin in breast cancer patients. This agent does not alter the anticancer effect of doxorubicin. Its mode of action suggests a chelation of free radicals. In mice, dexrazoxane also offers protection against cardiac side effects of epirubicin, but not mitoxantrone.

Cardioprotectant.

Safety

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H315-H319-H335
Precautionary statements	P261-P264-P271-P280-P302+P352-P305+P351+P338
Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	26-36
RIDADR	UN 2811 6.1 / PGIII
WGK Germany	3
RTECS	TL6390000
HS Code	2933.59.9500