Salinomycinsodiumsalt , ≥98% , 55721-31-8
CAS NO.：55721-31-8
Empirical Formula: C42H71NaO12
Molecular Weight: 791
MDL number: MFCD00145265
EINECS: 611-309-0
| Pack Size | Price | Stock | Quantity |
| 25mg | RMB412.80 | In Stock |
|
| 50mg | RMB696.00 | In Stock |
|
| 100mg | RMB1174.40 | In Stock |
|
| others | Enquire |
PRODUCT Properties
| Melting point: | 140-142° |
| alpha | D25 -37° (c = 1 in ethanol) |
| storage temp. | APPROX 4°C |
| solubility | Soluble in DMSO. |
| form | Solid |
| color | White |
| Merck | 13,8415 |
| BRN | 4901827 |
| Stability: | Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months. |
Description and Uses
Salinomycin Na (55721-31-8) is a polyether ionophore with antibiotic and anti-cancer properties. It induces cell death in some types of cancer cells such as breast, lung, gastric cancer, leukemia and osteosarcoma.1?Salinomycin Na displays selective toxicity for cancer stem cells.1?Induces rapid mitochondrial hyperpolarization.2?Induces selective cytotoxicity to MCF-7 mammosphere cells via the hedgehog signaling pathway.3?Salinomycin Na reduces doxorubicin resistance of breast tumor cells by inhibiting drug efflux pump expression and activity.4?Kills cancer stem cells by sequestering iron.5
Salinomycin is an ionophore agent.
