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M5288335

Ripasudilfreebase , 98% , 223645-67-8

CAS NO.:223645-67-8

Empirical Formula: C15H18FN3O2S

Molecular Weight: 323.39

MDL number:

Pack Size Price Stock Quantity
2mg RMB966.40 In Stock
5mg RMB1459.20 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Boiling point: 497.2±55.0 °C(Predicted)
Density  1.293±0.06 g/cm3(Predicted)
storage temp.  under inert gas (nitrogen or Argon) at 2–8 °C
solubility  Soluble in DMSO
pka 9.70±0.40(Predicted)

Description and Uses

Ripasudil (Glanatec TM, Kowa Pharmaceutical), a close derivative of fasudil, is another Rho kinase inhibitor approved in Japan at the end of 2014 for the treatment of glaucoma and ocular hypertensionwhen other therapeutic agents are not effective or cannot be administered. Additionally, ripasudil has been tested in diabetic retinopathy clinical trials and shown to promote corneal endothelial cell proliferation, endothelium regeneration, and wound healing.

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338

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