PRODUCT Properties
Melting point: | 110 °C (decomp) |
Boiling point: | 802.6±65.0 °C(Predicted) |
Density | 1.21±0.1 g/cm3(Predicted) |
storage temp. | -20°C Freezer |
solubility | DMSO (Slightly), Methanol (Slightly) |
pka | pKa 8.84(H2O,t =25,I=0.167) (Uncertain) |
form | Solid |
color | White to Off-White |
Description and Uses
Oleandomycin is a 16-membered macrocyclic lactone, discovered in the 1950s, with broad spectrum antibacterial activity. Oleandomycin was developed as a human pharmaceutical but was regarded as less active than comparable products such as erythromycin and is today only available in combination with other antibiotics.
Safety
Toxicity | LD50 orl-rat: 6700 mg/kg AMPMAR 39,259,1978 |