PRODUCT Properties
| Melting point: | 128-145 °C |
| storage temp. | Sealed in dry,2-8°C |
| solubility | ethanol: 50 mg/mL, clear to slightly hazy, light-yellow |
| form | Solid |
| color | White to Off-White |
| Merck | 14,5453 |
| CAS DataBase Reference | 1392-21-8 |
Description and Uses
Kitasamycin, formerly called leucomycin, was found in the culture broth of Streptoverticillium kitasatoensis by Hata et al. of the Kitasato Institute, Japan, in 1953. This was the first macrolide antibiotic with a 16-membered lactone constituent. Kitasamycin is a complex of eight leucomycin A components and is used in its base and ester forms to treat gram-positive bacterial and gram-negative coccal infections, as well as infections of Mycoplasma, Spirochaeta, and Treponema by injection or by oral topical administration.
Leucomycins (>85%) (cas# 1392-21-8) is a compound useful in organic synthesis.
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H302 |
| Precautionary statements | P264-P270-P301+P312-P501 |
| Safety Statements | 24/25 |
| WGK Germany | 1 |
| RTECS | WG9400000 |
| F | 10 |
| HS Code | 29419090 |
| Toxicity | mouse,LD50,intraperitoneal,1758mg/kg (1758mg/kg),Drugs in Japan Vol. -, Pg. 354, 1995. |
