PRODUCT Properties
| Melting point: | 170 °C |
| alpha | D25 -23° (methanol) |
| Boiling point: | 757°C (rough estimate) |
| Density | 1.1651 (rough estimate) |
| refractive index | 1.6220 (estimate) |
| storage temp. | 0-6°C |
| solubility | Soluble in DMSO (up to 50 mg/ml) or in Ethanol (up to 25 mg/ml). |
| form | White solid. |
| pka | 6.6(at 25℃) |
| color | White |
| Water Solubility | 0.25g/L(28 ºC) |
| Merck | 13,9839 |
| Stability: | Stable for 2 years as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months. |
Description and Uses
Troleandomycin (2751-09-9) is a macrolide antibiotic. Inhibits cytochrome P450 (IC50 = 0-5 μM), thus blocking CYP450-dependent drug oxidation.
Antibacterial.
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H332-H315-H319 |
| Precautionary statements | P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P-P261-P271-P304+P340-P312 |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 22-24/25-36-26 |
| WGK Germany | 2 |
| RTECS | RJ9900000 |
| F | 8 |
| Toxicity | LD50 oral in mouse: > 5gm/kg |
