PRODUCT Properties
| Melting point: | 225-228 °C(Solv: methanol (67-56-1); benzene (71-43-2)) |
| Boiling point: | 508.5±50.0 °C(Predicted) |
| Density | 1.13±0.1 g/cm3(Predicted) |
| Flash point: | 93 °C |
| storage temp. | 2-8°C |
| solubility | Acetonitrile: 1 mg/ml; Ethanol: 1 mg/ml; Methanol: 1 mg/ml |
| pka | 14.95±0.70(Predicted) |
| form | White to off-white solid. |
| color | White to off-white |
| EPA Substance Registry System | Pregn-5-ene-16-carbonitrile, 3-hydroxy-20-oxo-, (3.beta.,16.alpha.)- (1434-54-4) |
Description and Uses
Pregnenolone Carbonitrile is a glucocorticoid receptor antagonist that induces the expression of the CYP3A family of steroid hydroxylases and modulates sterol and bile acid biosynthesis in vivo. Pregnenolone Carbonitrile is an an activator of rat pregnane X receptor (PXR).
Safety
| WGK Germany | 3 |
| RTECS | TU4536500 |
