M4441553
Z-Guggulsterone , 98% , 39025-23-5
Synonym(s):
(Z)-Guggulsterone;(17Z)-Pregna-4,17(20)-diene-3,16-dione;4,17(20)-trans-Pregnadiene-3,16-dione
| Pack Size | Price | Stock | Quantity |
| 5mg | RMB1359.20 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | 188-190° |
| alpha | D26 -61° (c = 1 in chloroform) |
| Boiling point: | 463.3±45.0 °C(Predicted) |
| Density | 1.10±0.1 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | DMSO: 5 mg/mL |
| form | powder |
| color | light yellow |
| Stability: | Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months. |
| InChI | InChI=1S/C21H28O2/c1-4-16-19(23)12-18-15-6-5-13-11-14(22)7-9-20(13,2)17(15)8-10-21(16,18)3/h4,11,15,17-18H,5-10,12H2,1-3H3/b16-4+/t15-,17+,18+,20+,21-/m1/s1 |
| InChIKey | WDXRGPWQVHZTQJ-OSJVMJFVSA-N |
| SMILES | C1(=O)C=C2[C@](C)(CC1)[C@]1([H])[C@]([H])([C@@]3([H])[C@@](CC1)(C)/C(=C/C)/C(=O)C3)CC2 |
| LogP | 3.650 (est) |
Description and Uses
Guggulsterone-(Z) (39025-23-5) is a natural steroid from?Commiphora mukul?extract (guggulipid) which lowers cholesterol and acts as an FXR antagonist.1?Attenuates astrocyte-mediated neuroinflammation.2? Induces differentiation of pluripotent stem cells to dopaminergic neurons.3 Produces antidepressant-like effects via activation of the BDNF signaling pathway in mouse models.4
(Z)-Guggulsterone acts as an α-glucosidase inhibitor also known as a hypolipidemic agent.
