M3448135
Lasalocid , 98% , 25999-31-9
CAS NO.:25999-31-9
Empirical Formula: C34H54O8
Molecular Weight: 590.79
MDL number:
EINECS: 247-401-9
Pack Size | Price | Stock | Quantity |
5mg | RMB2616.00 | In Stock |
|
others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
Melting point: | 110-114°; mp 100-109° (unsharp) |
alpha | D25 -7.55° (methanol) |
Boiling point: | 735.7±60.0 °C(Predicted) |
Density | 1.119±0.06 g/cm3(Predicted) |
storage temp. | -20°C Freezer, Under inert atmosphere |
solubility | Acetonitrile,(Slightly), Methanol (Slightly, Sonicated) |
form | Solid |
pka | 3.15±0.39(Predicted) |
color | White to Off-White |
Description and Uses
Lasalocid is an ionophore antibiotic isolated from certain Streptomyces sp. and used in veterinary practice as a coccidiostat for gastrointestinal parasites. Lasalocid cytotoxicity targets cell metabolism, demonstrating EC50 values in the range of 7-
Lasalocid is an anticancer supplement agent comprising of polyether antibiotic for treating brain tumors, also inhibits mitochondrial GPD2 activity and elicits anti-proliferative effects on cancer cells.
Safety
Toxicity | LD50 in mice (mg/kg): 40 i.p. (Berger); also reported as LD50 in mice (mg/kg): 146 orally, 64 i.p., J. W. Westley, "Antibiotics (Polyether)" in Kirk-Othmer Encyclopedia of Chemical Technology Vol. 3 (Interscience, New York, 3rd ed., 1978) p 61 |