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A6945658

Anacardicacid , 10mMinDMSO , 16611-84-0

Synonym(s):
22:0-Anacardic acid;2-Hydroxy-6-pentadecylbenzoic acid;6-Pentadecylsalicylic acid;Anacardic acid

CAS NO.:16611-84-0

Empirical Formula: C22H36O3

Molecular Weight: 348.52

MDL number: MFCD07368254

Pack Size Price Stock Quantity
1ml RMB554.40 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 90-91℃
Boiling point: 474.8±33.0 °C(Predicted)
Density  1.002
storage temp.  -20°C
solubility  DMSO: ≥20mg/mL
form  White solid
pka 3.08±0.30(Predicted)
color  white to beige
Stability: Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
InChIKey ADFWQBGTDJIESE-UHFFFAOYSA-N
LogP 9.960 (est)

Description and Uses

Anacardic acid, isolated from cashew shells or several other medicinal plants, is the general name given to a family of four different 6-alkyl salicyclic acids having varying degrees of unsaturation in the 15-carbon alkyl chain. These compounds are associated with anti-inflammatory, anti-tumor, molluscicidal, and anti-microbial activity. Literature frequently sites and gives the name anacardic acid to the completely-saturated compound (6-pentadecyl salicylic acid). Anacardic acid inhibits the histone acetyltransferase (HAT) activity of the transcription co-activators p300 and p300/CREB-binding protein-associated factor (PCAF) with IC50 values of 8.5 and 5 μM, respectively. At 25 μmol/L, anacardic acid suppresses NF-κB activation, inhibits IκB-α phosphorylation, and prohibits p65 nuclear translocation in KBM-5 cells.

2-Hydroxy-6-pentadecyl Benzoic Acid, is a compound that is used to treat agriculture from various fruit insects. Derivative of this molecule has been also shown to be a potent activator of human 5-lipoxygenases (5-LOX).

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319
Precautionary statements  P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313
Hazard Codes  Xi
Risk Statements  36
Safety Statements  26
WGK Germany  3

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