SGC-CBP30 , 99% , 1613695-14-9

Synonym(s):
2-[2-(3-Chloro-4-methoxyphenyl)ethyl]-5-(3,5-dimethyl-1,2-oxazol-4-yl)-1-[(S)-2-(morpholin-4-yl)propyl]-1H-benzimidazole

CAS NO.：1613695-14-9

Empirical Formula: C28H33ClN4O3

Molecular Weight: 509.04

MDL number: MFCD26792586

Pack Size	Price	Stock	Quantity
5mg	RMB1027.20	In Stock
others			Enquire

Update time: 2022-07-08

PRODUCT Properties

Boiling point:	678.0±55.0 °C(Predicted)
Density	1.28±0.1 g/cm3(Predicted)
storage temp.	2-8°C
solubility	≥20.05 mg/mL in DMSO; ≥25.7 mg/mL in EtOH with ultrasonic; ≥4.67 mg/mL in H2O with ultrasonic
pka	6.98±0.10(Predicted)
form	powder
color	white to beige

Description and Uses

SGC-CBP30 is a potent CBP/p300 bromodomain (BRD) inhibitor. SGC-CBP30 shows Kd values are 21 and 32 nM for CBP and p300 BRDs respectively. SGC-CBP30 also exhibits 40-fold and 250-fold selectivity for CBP over the first BRD of BRD4 (BRD4(1)) and BRD4(2) respectively. SGC-CBP30 accelerates FRAP recovery in cells at a concentration of 1 ?M.

SGC-CBP30 is a potent CREBBP/EP300 inhibitor.