Eprosartan , ≥95% , 133040-01-4

CAS NO.：133040-01-4

Empirical Formula: C23H24N2O4S

Molecular Weight: 424.51

MDL number: MFCD00897872

PRODUCT Properties

• Melting point: 250-253°C
• storage temp.: Sealed in dry,2-8°C
• solubility: Dichloromethane (Slightly), Methanol (Slightly)
• form: Solid
• color: Pale Yellow to Light Yellow

Description and Uses

Teveten was launched in Germany for the treatment of hypertension. There are several ways in which it has been prepared, the shortest of which is four steps; beginning with displacement of 2-butyl-4-chloroimidazole-5-carboxaldehyde with methyl 4-(bromomethyl)benzoate. Teveten is an angiotensin Ⅱ antagonist selective for the AT, subtype receptor. It is a potent, highly selective, competitve antagonist with no agonist activity. Duration of action is similar to Enalapril (greater than 12 hr) but Teveten had a faster onset. While it is orally active, it rapidly dissociates from the receptor. This is contrary to its prolonged duration of action, which presumably results from slow removal from compartments within tissue, cells or matrix around the AT, receptor. It is not bound by BSA.

Prototype of the imidazoleacrylic acid angiotensin II receptor antagonists. Antihypertensive

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H315-H319
• Precautionary statements: P305+P351+P338