Cyclo(L-Phe-L-Pro) , 95% , 3705-26-8

CAS NO.：3705-26-8

Empirical Formula: C14H16N2O2

Molecular Weight: 244.29

MDL number: MFCD00038604

EINECS: 223-047-0

PRODUCT Properties

• Melting point: 146-148 °C
• Boiling point: 509.5±39.0 °C(Predicted)
• Density: 1.26±0.1 g/cm3(Predicted)
• storage temp.: -15°C
• solubility: Chloroform (Slightly), Ethanol (Slightly, Sonicated)
• form: Solid
• pka: 13.21±0.40(Predicted)
• color: White to Off-White
• Stability: Hygroscopic

Description and Uses

Cyclo(L-Phe-L-Pro) is a diketopiperazine formed by the fusion of phenylalanine and proline, reported as a secondary metabolite of fungi and bacteria. In Pseudomonas aeruginosa, cyclo(L-Phe-L-Pro) is capable of activating N-acylhomoserine lactones (AHLs). Cyclo(L-Phe-L-Pro) is also capable of activating or antagonizing other LuxR-based quorum-sensing systems. While the mode of action of cyclo(L-Phe-L-Pro) is not known, its activity suggests the existence of cross talk among bacterial signalling systems.