Maculosin , ≥98% , 4549-02-4

CAS NO.：4549-02-4

Empirical Formula: C14H16N2O3

Molecular Weight: 260.29

MDL number: MFCD03093467

PRODUCT Properties

• Melting point: 156-159 °C
• Boiling point: 581.4±43.0 °C(Predicted)
• Density: 1.36±0.1 g/cm3(Predicted)
• storage temp.: -15°C
• solubility: DMF: soluble; DMSO: soluble; Ethanol: soluble; Methanol: soluble
• form: A solid
• pka: 9.92±0.15(Predicted)
• color: White to off-white

Description and Uses

Maculosin is a diketopiperazine metabolite produced by A. alternata, L. capsici, Streptomyces, and the Gram-negative, nonobligate predator bacterial strain 679-2. It acts as a host-specific phytotoxin, inducing formation of weeping necrotic lesions in leaves of spotted knapweed (C. maculosa) when used at a concentration of 10 μM. Maculosin reduces the growth of the plant pathogenic bacteria X. axonopodis and R. solanacearum (MICs = 31.25 μg/ml) as well as the pathogenic oomycetes P. cactorum, P. capsici, P. cinnamomi, P. infestans, and P. ultimum when used at concentrations ranging from 10 to 100 mg/ml. Maculosin also inhibits the growth of M. luteus, M. smegmatis, S. cerevisiae, C. albicans, C. neoformans, and A. niger when used in combination with pyrrolnitrin or banegasin.

Cyclo(L-prolinyl-L-tyrosine) is a diketopiperazine derivative isolated from Bacillus thuringiensis and Bacillus endophyticus.

Safety

• Symbol(GHS): GHS08,GHS06
• Signal word: Danger
• Hazard statements: H301-H311-H331-H371
• Precautionary statements: P280-P302+P352-P312-P322-P361-P363-P405-P501-P260-P264-P270-P309+P311-P405-P501-P264-P270-P301+P310-P321-P330-P405-P501-P261-P271-P304+P340-P311-P321-P403+P233-P405-P501