(±)-N-3-Benzylnirvanol , ≥98% , 93879-40-4

CAS NO.：93879-40-4

Empirical Formula: C18H18N2O2

Molecular Weight: 294.35

MDL number: MFCD07353973

PRODUCT Properties

• Melting point: 134-136°C
• Density: 1.190±0.06 g/cm3(Predicted)
• storage temp.: -20°C Freezer
• solubility: DMSO (Slightly), Methanol (Slightly)
• pka: 8.02±0.70(Predicted)
• form: Solid
• color: White to Off-White

Description and Uses

(±)-N-3-Benzylnirvanol is a racemic mixture of (+)-N-3-benzylnirvanol and (–)-N-3-benzylnirvanol. (+)-N-3-benzylnirvanol and (–)-N-3-benzylnirvanol are inhibitors of the cytochrome P450 (CYP) isoform CYP2C19 (K_is = 0.25 and 5.3 μM, respectively). (±)-N-3-Benzylnirvanol (20 mg/kg, i.p.) lowers plasma levels of cholesterol in mice.

It is a potent and selective human CYP2C19 inhibitor

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H302-H315-H319-H335
• Precautionary statements: P261-P264-P270-P271-P280-P301+P312-P330-P302+P352-P321-P304+P340-P305+P351+P338-P332+P313-P362+P364-P337+P313-P403+P233-P405-P501