1,4-DPCA , ≥98% , 331830-20-7
| Pack Size | Price | Stock | Quantity |
| 10mg | RMB1021.60 | In Stock |
|
| 25mg | RMB2298.40 | In Stock |
|
| 50mg | RMB4536.00 | In Stock |
|
| others | Enquire |
PRODUCT Properties
| Boiling point: | 419.5±45.0 °C(Predicted) |
| Density | 1.52±0.1 g/cm3(Predicted) |
| storage temp. | RT |
| solubility | Soluble in DMSO (up to 15 mg/ml with warming). |
| form | Tan solid. |
| pka | 2.55±0.20(Predicted) |
| color | Off-white |
| Stability: | Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 2 months. |
Description and Uses
1,4-DPCA (331830-20-7) is a potent inhibitor of prolyl 4-hydroxylase (IC50=2-4 μM).1 Inhibits collagen deposition via inhibition of collagen proline hydroxylation.2,3 Subcutaneous injection of a 1,4-DPCA containing hydrogel into Swiss Webster mice that do not show a regenerative phenotype increased expression of HIF1α over 5 days. Multiple injections led to regenerative wound healing after ear hole punch injury.4
1,4-DPCA nis a potent competitive inhibitor of avian prolyl 4-hydroxylase in embryonic chick tendon cells and human foreskin fibroblasts in vitro. It is a promotor of wound healing and tissue regeneration in mice.
