D-erythro-Sphinganine , ≥98% , 3102-56-5

Synonym(s):
Sphinganine

CAS NO.：3102-56-5

Empirical Formula: C18H39NO2

Molecular Weight: 301.51

MDL number: MFCD00079141

EINECS: 608-571-3

PRODUCT Properties

• Melting point: 70-72°C
• Boiling point: 446.2±25.0 °C(Predicted)
• Density: 0.927±0.06 g/cm3(Predicted)
• storage temp.: −20°C
• solubility: chloroform/methanol (9:1): 20 mg/mL, clear, colorless to faintly yellow
• form: Solid
• pka: 12.57±0.45(Predicted)
• color: white
• Water Solubility: Soluble in water (partly miscible), chloroform, 100% warm ethanol (25 mg/ml), warm DMSO (25 mg/ml), and methanol.
• InChI: InChI=1/C18H39NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-18(21)17(19)16-20/h17-18,20-21H,2-16,19H2,1H3/t17-,18+/s3
• InChIKey: OTKJDMGTUTTYMP-LHIQYTEENA-N
• SMILES: C(O)[C@@H](N)[C@@H](O)CCCCCCCCCCCCCCC |&1:2,4,r|

Description and Uses

DL-erythro Sphinganine (d18:0) is a precursor of ceramide and sphingosine as well as a substrate of sphingosine kinases, which generate sphinganine-1-phosphate . Sphinganine levels increase significantly in response to certain mycotoxins, including fumonisins as well as in some cancers. This product is a mixture of sphinganine (d18:0) , L-erythro sphinganine (d18:0) , D-threo sphinganine (d18:0) , and L-threo sphinganine (d18:0). [Matreya, LLC. Catalog No. 1324]

Biosynthetic precursor of sphingosine. Inhibits protein kinase C

Safety

• WGK Germany: 3