1,9-Dideoxyforskolin , ≥98% , 64657-18-7
Synonym(s):
7β-Acetoxy-6β-hydroxy-8,13-epoxy-labd-14-en-11-one;7β-Acetoxy-8,13-epoxy-6β-hydroxy-labd-14-en-11-one;Forskolin, 1,9-Dideoxy-, Coleus forskohlii - CAS 64657-18-7 - Calbiochem
Pack Size | Price | Stock | Quantity |
500ug | RMB1052.00 | In Stock |
|
1mg | RMB1612.00 | In Stock |
|
5mg | RMB6392.00 | In Stock |
|
others | Enquire |
PRODUCT Properties
Melting point: | 149-150℃ |
storage temp. | −20°C |
solubility | methanol: 28 mg/mL |
form | solid |
color | white |
optical activity | [α]26/D +93.6°, c = 6.12 in chloroform(lit.) |
InChIKey | ZKZMDXUDDJYAIB-OJPJTMFRSA-N |
Description and Uses
Forskolin is a naturally-occurring diterpene that activates adenylyl cyclase through its catalytic subunit and is commonly used to raise levels of cAMP in a wide variety of intact cells and tissue preparations. 1,9-dideoxy Forskolin is an analog of forskolin that interacts with, but does not activate, adenylyl cyclase.
1,9-Dideoxyforkskolin does not activate adenylyl cyclase and is an inactive analog of Forskolin (F701800), a diterpene isolated from Coleus forskohlii, possessing vasodilating and cardiostimulatory properties. Forskolin resensitizes cell receptors by activating the enzyme adenylyl cyclase and increasing the intracellular levels of cAMP.
Safety
Symbol(GHS) | GHS07 |
Signal word | Warning |
Hazard statements | H312 |
Precautionary statements | P280-P302+P352-P312-P322-P363-P501 |
WGK Germany | 3 |