Home Categories Analytical Chemistry 1,9-Dideoxyforskolin
LN3887949

1,9-Dideoxyforskolin , ≥98% , 64657-18-7

Synonym(s):
7β-Acetoxy-6β-hydroxy-8,13-epoxy-labd-14-en-11-one;7β-Acetoxy-8,13-epoxy-6β-hydroxy-labd-14-en-11-one;Forskolin, 1,9-Dideoxy-, Coleus forskohlii - CAS 64657-18-7 - Calbiochem

CAS NO.:64657-18-7

Empirical Formula: C22H34O5

Molecular Weight: 378.5

MDL number: MFCD00082318

Pack Size Price Stock Quantity
500ug RMB1052.00 In Stock
1mg RMB1612.00 In Stock
5mg RMB6392.00 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 149-150℃
storage temp.  −20°C
solubility  methanol: 28 mg/mL
form  solid
color  white
optical activity [α]26/D +93.6°, c = 6.12 in chloroform(lit.)
InChIKey ZKZMDXUDDJYAIB-OJPJTMFRSA-N

Description and Uses

Forskolin is a naturally-occurring diterpene that activates adenylyl cyclase through its catalytic subunit and is commonly used to raise levels of cAMP in a wide variety of intact cells and tissue preparations. 1,9-dideoxy Forskolin is an analog of forskolin that interacts with, but does not activate, adenylyl cyclase.

1,9-Dideoxyforkskolin does not activate adenylyl cyclase and is an inactive analog of Forskolin (F701800), a diterpene isolated from Coleus forskohlii, possessing vasodilating and cardiostimulatory properties. Forskolin resensitizes cell receptors by activating the enzyme adenylyl cyclase and increasing the intracellular levels of cAMP.

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H312
Precautionary statements  P280-P302+P352-P312-P322-P363-P501
WGK Germany  3

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