LN3715749
1,4-PBIT(dihydrobromide) , ≥98% , 157254-60-9
CAS NO.:157254-60-9
Empirical Formula: C12H20Br2N4S2
Molecular Weight: 444.25
MDL number: MFCD00797677
Pack Size | Price | Stock | Quantity |
50mg | RMB900.00 | In Stock |
|
100mg | RMB1592.00 | In Stock |
|
500mg | RMB6964.00 | In Stock |
|
others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
Melting point: | 234-236 °C |
storage temp. | −20°C |
solubility | DMF: 20 mg/ml; DMSO: 25 mg/ml; PBS (pH 7.2): 5 mg/ml |
form | White to off-white powder. |
Description and Uses
1,4-PBIT is a potent inhibitor of purified human iNOS and nNOS with Ki values of 7.4 and 16 nM, respectively, compared to a Ki of 360 nM for human eNOS. Its inhibition in whole cells is greatly diminished, presumably to poor membrane permeability.