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LN-134792

Centchroman , 99% , 31477-60-8

CAS NO.:31477-60-8

Empirical Formula: C30H35NO3

Molecular Weight: 457.6

MDL number:

Update time: 2023-04-23

PRODUCT Properties

Melting point: 99-101°
Boiling point: 563.39°C (rough estimate)
Density  1.1065 (rough estimate)
refractive index  1.6310 (estimate)
storage temp.  2-8°C
solubility  Soluble in DMSO
pka 9.61±0.20(Predicted)
form  oil
color  colorless to light brown

Description and Uses

Centchroman is a new, weekly, orally active contraceptive with weak estrogenic and potent antiestrogenic properties.It is reported to be the first non-hormonal, non-steroidal oral contraceptive. Centchroman acts by inhibiting the implantation of fertilized eggs in the uterus. With the exception of longer menstrual cycles, no side effects have been reported. Another indication under study is the treatment of hormone dependent breast cancer.

Centchroman is an estrogen antagonist. Centchroman is a synthetic nonsteroidal postcoital antifertility agent.

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