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BD8778247

Sauchinone , 97% , 177931-17-8

Synonym(s):
(5aα,7α,8β,8aβ,14aS*,14bβ)-5a,6,7,8,8a,14b-Hexahydro-7,8-dimethyl-5H-benzo[kl]bis[1,3]dioxolo[4,5-b:4′,5′-g]xanthen-5-one;(5aR,7R,8S,8aR,14aS,14bR)-5a,6,7,8,8a,14b-Hexahydro-7,8-dimethyl-5H-Benzo[kl]bis[1,3]dioxolo[4,5-b:4′,5′-g]xanthen-5-one

CAS NO.:177931-17-8

Empirical Formula: C20H20O6

Molecular Weight: 356.37

MDL number: MFCD08702698

Pack Size Price Stock Quantity
100mg RMB3120.00 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 224-226℃
Boiling point: 498.1±45.0 °C(Predicted)
Density  1.43±0.1 g/cm3 (20 ºC 760 Torr)
storage temp.  2-8°C
solubility  DMSO: soluble5mg/mL, clear (warmed)
form  powder
color  white to beige

Description and Uses

Sauchinone is a lignan first isolated from the aerial parts of S. chinensis, a plant used in Asian medicine for its anti-inflammatory, anti-angiogenic, and anti-nociceptive activities. Sauchinone has numerous effects on isolated cells, including blocking NF-κB activation in LPS-stimulated macrophages, inducing heme oxygenase-1 transcription in endothelial cells, and attenuating oxidative-stress-induced damage in myoblasts. Sauchinone is extensively metabolized in vivo, but intraperitoneal administration significantly reduces myocardial infarct size induced by ischemia/reperfusion in mice.

Safety

Safety Statements  24/25
WGK Germany  3
HS Code  29329990

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