BD8591531
Sirtinol , 98% , 410536-97-9
Synonym(s):
2-[(2-Hydroxynaphthalen-1-ylmethylene)amino]-N-(1-phenethyl)benzamide;2-[(2-Hydroxynaphthalen-1-ylmethylene)amino]-N-(1-phenethyl)benzamide, Sir Two Inhibitor Naphthol, SIRT1 Inhibitor I, SIRT1/2 Inhibitor I, SIRT2 Inhibitor III;Sirtinol - CAS 410536-97-9 - Calbiochem
| Pack Size | Price | Stock | Quantity |
| 1mg | RMB101.60 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | 119-120℃ |
| Boiling point: | 659.2±50.0 °C(Predicted) |
| Density | 1.16 |
| storage temp. | -20°C |
| solubility | Soluble in DMSO (up to 30 mg/ml). |
| form | Yellow solid |
| pka | 7.85±0.50(Predicted) |
| color | Pale yellow |
| Water Solubility | Soluble in water, DMSO and methanol |
| Stability: | Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month. |
Description and Uses
Sirtinol (410536-97-9) is an inhibitor of sirtuin family enzymes including human SIRT1 (IC50=60 μM), human SIRT2 (IC50=58 μM), and yeast Sir2 (IC50=48 μM) with no inhibition of human HDAC1. Active in vivo and in purified enzyme studies. Cell permeable.
Sirtinol is a cell permeable specific inhibitor of sirtuin NAD-dependant deacetylases
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a |
| WGK Germany | 3 |
