(5S,8S,11S)-5,8-Diisobutyl-11-((4-methyl-2-oxo-2H-chromen-7-yl)carbamoyl)-3,6,9-trioxo-1-phenyl-2-oxa-4,7,10-triazatetradecan-14-oicacid , 97% , 348086-66-8
Synonym(s):
Cbz-Leu-Leu-Glu-AMC;Z-LLE-AMC
| Pack Size | Price | Stock | Quantity |
| 100mg | RMB4504.80 | In Stock |
|
| others | Enquire |
PRODUCT Properties
| Boiling point: | 967.8±65.0 °C(Predicted) |
| Density | 1.253±0.06 g/cm3(Predicted) |
| storage temp. | -20°C |
| solubility | DMSO: soluble |
| form | solid |
| pka | 4.43±0.10(Predicted) |
| color | Solid lyophilized powder |
Description and Uses
Z-LLE-AMC is a fluorogenic substrate for the caspase-like post-glutamate peptide hydrolase of the 26S proteasome or 20S proteolytic core. Caspase-like activity can be quantified by fluorescent detection of free AMC (also known as 7-amino-4-methylcoumarin), which is excited at 340-360 nm and emits at 440-460 nm. Z-LLE-AMC is typically used in cell lysates after experimental treatment.
A fluorogenic substrate for the peptidylglutamyl-peptide hydrolysing (caspase-like) activity of the proteasome which may be stimulated in the presence of Mg2+ ions and rapidly inactivated by N-acetylimidazole
Safety
| Safety Statements | 22-24/25 |
| WGK Germany | 3 |
