BD2869148
(R)-3-Mercapto-2-(2-mercapto-2-methylpropanamido)propanoicacid , 95% , 65002-17-7
| Pack Size | Price | Stock | Quantity |
| 1g | RMB4313.60 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | 119-123°C |
| alpha | D25 +32.3° (c = 1.0 in ethanol) |
| Boiling point: | 438.0±45.0 °C(Predicted) |
| Density | 1.3934 (rough estimate) |
| refractive index | 1.6370 (estimate) |
| storage temp. | Hygroscopic, -20°C Freezer, Under Inert Atmosphere |
| solubility | DMSO (Very Slightly), Ethanol (Slightly), Methanol (Slightly), Water (Slightly) |
| pka | 3.01±0.10(Predicted) |
| form | Solid |
| color | White to Pale Yellow |
| Stability: | Air Sensitive, Hygroscopic, Unstable in Solution |
| CAS DataBase Reference | 65002-17-7(CAS DataBase Reference) |
Description and Uses
Bucillamine is an orally active immunomodulator useful in the treatment of rheumatoid arthritis. Its potencies in inhibiting collagenase activity and inactivating rheumatoid factor far exceed those of penicillamine. In man, bucillamine reportedly brings about significant improvements over placebo in erythrocyte sedimentation, grip power, joint swelling and duration of morning stiffness.
An antirheumatic agent.
Safety
| Toxicity | LD50 in mice (mg/kg): 2285 i.p.; 989.6 i.v. (Fujita, 1981) |
