A5392712
N-(2-Mercaptopropionyl)glycine , 98% , 1953-02-2
Synonym(s):
Tiopronin
CAS NO.：1953-02-2
Empirical Formula: C5H9NO3S
Molecular Weight: 163.19
MDL number: MFCD00004861
EINECS: 217-778-4
| Pack Size | Price | Stock | Quantity |
| 5G | RMB129.60 | In Stock |
|
| 25G | RMB428.80 | In Stock |
|
| 100G | RMB1564.00 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | 93-98 °C |
| Boiling point: | 418.3±30.0 °C(Predicted) |
| Density | 1.249 (estimate) |
| refractive index | 1.5216 (estimate) |
| storage temp. | Inert atmosphere,2-8°C |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| pka | 3.36±0.10(Predicted) |
| form | solid |
| color | White |
| Merck | 14,9453 |
| BRN | 1859822 |
Description and Uses
Tiopronin is a sulfiydryl derivative of N-propylglycine useful in the treatment of cystine urolithiasis in children. It is also reportedly effective in the management of rheumatoid polyarthritis, possibly due to its inhibitory effect on the free oxygen radicals produced by inflammatory macrophages and granulocytes.
N-(2-Mercaptopropionyl)glycine or Tiopronin has been used:
- in the preparation of polyethylenimine (PEI)-coated gold microparticles (PEI-gold) for biolistic delivery of nucleic acids
- to study the role of reactive oxygen species (ROS) at the reperfusion stage in in vivo isoflurane preconditioning-induced neuroprotection
- as a ROS inhibitor to study its effect on lysophosphatidylcholine (LPC)-induced inflammasome activation
