BD2784445
N-(4-(Acridin-9-ylamino)-3-methoxyphenyl)methanesulfonamide , 98% , 51264-14-3
CAS NO.：51264-14-3
Empirical Formula: C21H19N3O3S
Molecular Weight: 393.46
MDL number: MFCD07799963
EINECS: 257-094-3
| Pack Size | Price | Stock | Quantity |
| 100mg | RMB1520.80 | In Stock |
|
| 250mg | RMB2586.40 | In Stock |
|
| 1g | RMB6984.00 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | 230-240 °C |
| Boiling point: | 563.0±60.0 °C(Predicted) |
| Density | 1.2205 (rough estimate) |
| refractive index | 1.6740 (estimate) |
| storage temp. | 2-8°C(protect from light) |
| solubility | Soluble in DMSO |
| form | Powder |
| pka | 8.55±0.10(Predicted) |
| color | Orange to red |
| CAS DataBase Reference | 51264-14-3 |
| IARC | 2B (Vol. 76) 2000 |
Description and Uses
Amsacrine is a cytostatic reported to be active against adult lymphoblastic leukemia which has failed primary treatment or become resistant. Its clinical use, however, is associated with significant neuro-, gastro- and hepatotoxicity.
Amsacrine (Amsidyl) is used as an Investigational drug.
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H315-H319-H227 |
| Precautionary statements | P501-P210-P264-P280-P302+P352-P370+P378-P337+P313-P305+P351+P338-P362+P364-P332+P313-P403+P235 |
| RIDADR | 3249 |
| HazardClass | 6.1(b) |
| PackingGroup | III |
| Hazardous Substances Data | 51264-14-3(Hazardous Substances Data) |
| Toxicity | LD50 in male, female CDF1 mice: 810 mg/m2; 729 mg/m2 orally (Pavkov) |
