BD0989432
Methyl 1-((2'-cyano-[1,1'-biphenyl]-4-yl)methyl)-2-ethoxy-1H-benzo[d]imidazole-7-carboxylate , 98% , 139481-44-0
CAS NO.:139481-44-0
Empirical Formula: C25H21N3O3
Molecular Weight: 411.45
MDL number: MFCD09031384
EINECS: 604-137-2
Pack Size | Price | Stock | Quantity |
5g | RMB35.20 | In Stock |
|
25g | RMB126.40 | In Stock |
|
100g | RMB488.00 | In Stock |
|
500g | RMB2405.60 | In Stock |
|
others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
Melting point: | 168 °C |
storage temp. | 2-8°C |
solubility | Chloroform (Slightly), Methanol (Slightly, Sonicated) |
form | Solid |
color | Off-White to Light Yellow |
InChI | InChI=1S/C25H21N3O3/c1-3-31-25-27-22-10-6-9-21(24(29)30-2)23(22)28(25)16-17-11-13-18(14-12-17)20-8-5-4-7-19(20)15-26/h4-14H,3,16H2,1-2H3 |
InChIKey | KSXLHOFDCDKQLH-UHFFFAOYSA-N |
SMILES | C1(OCC)N(CC2=CC=C(C3=CC=CC=C3C#N)C=C2)C2=C(C(OC)=O)C=CC=C2N=1 |
Description and Uses
Methyl 1-[(2'-cyanobiphenyl-4-yl)methyl]-2-ethoxy-1H-benzimidazole-7-carboxylate is a key synthetic intermediate in the synthesis of azilsartan, an angiotensin II.1 (AT1) receptor antagonist used in the treatment of hypertension.
Intermediate in the synthesis of angiotensin II receptor antagonist.
Safety
Symbol(GHS) | GHS07 |
Signal word | Warning |
Hazard statements | H319-H302-H315-H312-H332 |
Precautionary statements | P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362-P280-P302+P352-P312-P322-P363-P501-P264-P270-P301+P312-P330-P501-P261-P271-P304+P340-P312 |