Home Categories Natural Products Dihydromyricetin
A8463932

Dihydromyricetin , >97.0%(HPLC) , 27200-12-0

CAS NO.:27200-12-0

Empirical Formula: C15H12O8

Molecular Weight: 320.25

MDL number: MFCD00189451

EINECS: 200-001-8

Pack Size Price Stock Quantity
250mg RMB39.20 In Stock
1G RMB55.20 In Stock
5g RMB119.20 In Stock
25g RMB551.20 In Stock
50g RMB879.20 In Stock
100g RMB1519.20 In Stock
others     Enquire
Update time: 2022-07-08

PRODUCT Properties

storage temp.  -20°C
solubility  DMSO: ≥5mg/mL (warmed)
form  powder
Boiling point: 780.7±60.0 °C(Predicted)
Density  1.808±0.06 g/cm3(Predicted)
Melting point: 239-241 °C
pka 7.38±0.60(Predicted)
color  white to beige
Stability: Hygroscopic
InChI InChI=1S/C15H12O8/c16-6-3-7(17)11-10(4-6)23-15(14(22)13(11)21)5-1-8(18)12(20)9(19)2-5/h1-4,14-20,22H/t14-,15+/m0/s1
InChIKey KJXSIXMJHKAJOD-LSDHHAIUSA-N
SMILES [C@H]1(C2=CC(O)=C(O)C(O)=C2)OC2=CC(O)=CC(O)=C2C(=O)[C@@H]1O
LogP 1.230 (est)

Description and Uses

Dihydromyricetin (DHM), also known as ampelopsin, is a natural flavonoid compound, which is found in large quantities in Asian plant species. One of them – Hovenia dulcis – is known for centuries in traditional Chinese medicine as a cure for alcohol poisoning and hangover (Liang et al. 2014). DHM is sold as a supplement and is commonly marketed as a treatment for hangovers due to its ability to reduce blood alcohol levels and projected hepatoprotective properties.
Dihydromyricetin had beneficial effects on health such as antimicrobial, anti-inflammatory,antioxidative, anticancer, lipid and glucose metabolism-regulatory activities,and cell death-mediating without or with minimum adverse effects on normal cells. And most importantly, DHM has been shown to provide significant hepatoprotective effects. Its positive influence on alcohol-induced and other liver diseases was suggested in the study of acute liver failure (Liu et al. 2017).

Dihydromyricetin has been used to study its effect on adipogenesis and glucose uptake in differentiated 3T3-L1 pre-adipocytes. It has also been used to study its antitumor activity against liver cancer cells.

Safety

Safety Statements  24/25
WGK Germany  3
HS Code  29329990

RELATED PRODUCTS