Fustin , 98% , 20725-03-5
CAS NO.：20725-03-5
Empirical Formula: C15H12O6
Molecular Weight: 288.25
MDL number: MFCD00075647
EINECS: 243-989-6
| Pack Size | Price | Stock | Quantity |
| 5mg | RMB4656.00 | In Stock |
|
| others | Enquire |
PRODUCT Properties
| Melting point: | 216-217°C |
| storage temp. | -20°C |
| solubility | Acetone: soluble,Chloroform: soluble,Dichloromethane: soluble,DMSO: soluble,Ethyl Acetate: soluble |
| form | A solid |
| Boiling point: | 644.2±55.0 °C(Predicted) |
| Density | 1.599±0.06 g/cm3(Predicted) |
| pka | 7.59±0.60(Predicted) |
| color | White to off-white |
| LogP | 0.870 |
Description and Uses
Fustinis ((±)-Fustin; 3,7,3',4'-Tetrahydroxyflavanone) is a potent amyloid β (Aβ) inhibitor. Fustinis ((±)-Fustin; 3,7,3',4'-Tetrahydroxyflavanone) increases the expression of acetylcholine (ACh) levels, choline acetyltransferase (ChAT) activity, and ChAT gene induced by Aβ (1-42). Fustinis ((±)-Fustin; 3,7,3',4'-Tetrahydroxyflavanone) decreases in acetyl cholinesterase (AChE) activity and AChE gene expression induced by Aβ (1-42). Fustinis ((±)-Fustin; 3,7,3',4'-Tetrahydroxyflavanone) increases muscarinic M1 receptor gene expression and muscarinic M1 receptor binding activity. Fustinis ((±)-Fustin; 3,7,3',4'-Tetrahydroxyflavanone) can be used for Alzheimer's disease research[1].
