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A8359412

Voglibose , 98% , 83480-29-9

Synonym(s):
3,4-Dideoxy-4-{[2-hydroxy-1-(hydroxymethyl)ethyl]amino]-2-D-epi-inositol;N-(1,3-Dihydroxyprop-2-yl)valiolamine

CAS NO.:83480-29-9

Empirical Formula: C10H21NO7

Molecular Weight: 267.28

MDL number: MFCD00865496

EINECS: 1312995-182-4

Pack Size Price Stock Quantity
50mg RMB503.20 In Stock
100MG RMB599.20 In Stock
500MG RMB1891.20 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 162-163°C
alpha  D25 +26.2° (c = 1 in water)
Boiling point: 601.9±55.0 °C(Predicted)
Density  1.58±0.1 g/cm3(Predicted)
storage temp.  -20°C
solubility  DMSO (Slightly), Methanol (Very Slightly, Heated), Water (Sparingly, Sonicated)
form  Solid
pka 13.26±0.70(Predicted)
color  White to Off-White
Merck  14,10029
InChIKey FZNCGRZWXLXZSZ-CIQUZCHMSA-N
CAS DataBase Reference 83480-29-9(CAS DataBase Reference)

Description and Uses

Voglibose was introduced in Japan for the treatment of postprandial hyperglycemia in diabetic patients. As an orally active α-D-glucosidase inhibitor, it is effective in decreasing the release of glucose from carbohydrate ingestion and slowing the increase of postprandial blood glucose levels, as demonstrated in animals and humans following sucrose and starch loading. In addlion, voglibose was reported to have prophylactic effect in genetically obese Wistar rats, maintaining low plasma levels of glucose, triglyceride and insulin, indicating a potential usefulness for the management of other carbohydrate-dependent metabolic disorders such as obesity. Voglibose is much more potent and has fewer side effects than acarbose, another agent in its class.

For the treatment of diabetes. It is specifically used for lowering post-prandial blood glucose levels thereby reducing the risk of macrovascular complications.

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
Hazard Codes  Xi
Risk Statements  20/21/22-36/37/38
Safety Statements  36/37-37/39-26
WGK Germany  3
RTECS  NM7524600
HS Code  2940.00.6000

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