Miglitol , ≥98%(GC) , 72432-03-2

Synonym(s):
1-(2-Hydroxyethyl)-2-(hydroxymethyl)piperidine-3,4,5-triol

CAS NO.：72432-03-2

Empirical Formula: C8H17NO5

Molecular Weight: 207.22

MDL number: MFCD00867240

EINECS: 276-661-6

PRODUCT Properties

• Melting point: 114°C
• Boiling point: 453.7±45.0 °C(Predicted)
• Density: 1.458±0.06 g/cm3(Predicted)
• storage temp.: Sealed in dry,Store in freezer, under -20°C
• solubility: Soluble in DMSO (up to 50 mg/ml with warming), or in Water (up to 60 mg/ml).
• pka: 5.9(at 25℃)
• form: solid
• color: White
• Water Solubility: Soluble
• Merck: 14,6187
• Stability: Stable for 2 years from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20° for up to 1 month.
• InChIKey: IBAQFPQHRJAVAV-ULAWRXDQSA-N

Description and Uses

Miglitol was introduced in Germany as an auxiliary treatment for non-insulin dependent diabetes (NIDDM). A simple two-step synthesis of Miglitol consists of converting 6-desoxy-6-aminosorbose into desoxynojirimycin by reductive cyclization, then selectively hydroxyethylating the cyclic nitrogen. Miglitol is a short-acting intestinal alpha-D-glucosidase inhibitor, reducing postprandial glucose excursions by helping to delay absorption of complex carbohydrates. Acarbose and voglibose are the previous compounds marketed in this class. At low doses, orally administered miglitol was shown to be rapidly and completely absorbed then removed by renal excretion.

antibacterial

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H315-H319
• Precautionary statements: P305+P351+P338
• WGK Germany: 3
• RTECS: TN4350170
• HS Code: 29333990