Triisopropylsilyl Chloride , >95.0%(GC) , 13154-24-0
Synonym(s):
Chlorotriisopropylsilane;TIPSCl;Triisopropylchlorosilane;Triisopropylsilyl chloride
CAS NO.：13154-24-0
Empirical Formula: C9H21ClSi
Molecular Weight: 192.8
MDL number: MFCD00009656
EINECS: 603-492-0
| Pack Size | Price | Stock | Quantity |
| 5ML | RMB31.20 | In Stock |
|
| 10ml | RMB39.20 | In Stock |
|
| 25ML | RMB55.20 | In Stock |
|
| 50ML | RMB71.20 | In Stock |
|
| 100ML | RMB134.40 | In Stock |
|
| 500ML | RMB514.40 | In Stock |
|
| others | Enquire |
PRODUCT Properties
| Boiling point: | 198 °C739 mm Hg(lit.) |
| Density | 0.901 g/mL at 25 °C(lit.) |
| vapor pressure | 1.16 mm Hg ( 20 °C) |
| refractive index | n |
| Flash point: | 145 °F |
| storage temp. | Inert atmosphere,2-8°C |
| solubility | Sol THF, DMF, CH2Cl2. |
| form | liquid |
| Specific Gravity | 0.903 |
| color | colorless |
| Water Solubility | Miscible with water. |
| Sensitive | Moisture Sensitive |
| Hydrolytic Sensitivity | 8: reacts rapidly with moisture, water, protic solvents |
| BRN | 1737446 |
| InChIKey | KQIADDMXRMTWHZ-UHFFFAOYSA-N |
Description and Uses
Triisopropyl chlorosilane is an important sterically hindered organosilicon protective agent, which is mainly used to protect various types of hydroxyl groups, especially in polyfunctional hydroxyl compounds, which can be selectively protected and deprotected. It is very important to synthesize nucleosides, nucleotides and carbohydrates. Triisopropylchlorosilane is a good hydroxyl protecting agent, and its silanization reaction is carried out in a slight excess of imidazole solution. The acid hydrolytic stability of the protected intermediate is between TBDMS and TBDPS and the alkaline hydrolytic stability is higher than the former two.
Triisopropylsilyl chloride is used as a catalyst in the preparation of (silyloxy)cyclobutene derivatives. Also used in the addition of diethylzinc to N-diphenylphosphinoyl imines.
Safety
| Symbol(GHS) |  GHS05 |
| Signal word | Danger |
| Hazard statements | H314 |
| Precautionary statements | P280-P301+P330+P331-P303+P361+P353-P304+P340+P310-P305+P351+P338-P363 |
| Hazard Codes | C |
| Risk Statements | 34 |
| Safety Statements | 26-27-36/37/39-36/39 |
| RIDADR | UN 2987 8/PG 2 |
| WGK Germany | 3 |
| F | 10-21 |
| Hazard Note | Corrosive |
| TSCA | No |
| HazardClass | 8 |
| PackingGroup | II |
| HS Code | 29319090 |
