A7805312
Tipifarnib , 98% , 192185-72-1
Synonym(s):
(R)-(+)-R 115777;6-[(R)-Amino(4-chlorophenyl)(1-methyl-1H-imidazol-5-yl)methyl]-4-(3-chlorophenyl)-1-methyl-2(1H)-quinolinone;R115777
CAS NO.：192185-72-1
Empirical Formula: C27H22Cl2N4O
Molecular Weight: 489.4
MDL number: MFCD07772347
| Pack Size | Price | Stock | Quantity |
| 1MG | RMB231.20 | In Stock |
|
| 5mg | RMB799.20 | In Stock |
|
| 10MG | RMB1375.20 | In Stock |
|
| 25mg | RMB2879.20 | In Stock |
|
| 50MG | RMB4463.20 | In Stock |
|
| 100mg | RMB6911.20 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | 211-213°C (dec.) |
| Boiling point: | 681.7±55.0 °C(Predicted) |
| Density | 1.33±0.1 g/cm3(Predicted) |
| storage temp. | -20°C |
| solubility | Chloroform (Slightly), Methanol (Slightly) |
| pka | 7.20±0.10(Predicted) |
| form | powder |
| color | white to beige |
| optical activity | [α]/D 17 to 24°, c = 1 in methanol |
Description and Uses
A farnesyltransferase inhibitor. Sensitizes human multiple myeloma cell to proteasome inhibition by blocking degradation of bortezomib(B675700)-induced aggresomes. Also shown to inhibit the growth of myeloid leukemia cell lines and primary leukemia cells by inducing apoptosis and cell-cycle blockage when combined with rapamycin(R124000).
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P305+P351+P338 |
| HS Code | 2933790090 |
