A7767358
α-Estradiol , 10mMinDMSO , 57-91-0
Synonym(s):
1,3,5(10)-Estratriene-3,17α-diol;3,17α-Dihydroxy-1,3,5(10)-estratriene;Epiestradiol
CAS NO.：57-91-0
Empirical Formula: C18H24O2
Molecular Weight: 272.39
MDL number: MFCD00064144
EINECS: 200-354-8
| Pack Size | Price | Stock | Quantity |
| 1ml | RMB159.20 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | 176-180 °C(lit.) |
| Boiling point: | 355.44°C (rough estimate) |
| alpha | D20 +53 to +56° (c = 0.9 in dioxane) |
| Density | 1.0708 (rough estimate) |
| refractive index | 1.4800 (estimate) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | ethanol: 50 mg/mL, clear, colorless |
| form | powder |
| pka | 10.27±0.60(Predicted) |
| color | white with slight yellow |
| Water Solubility | 3.9mg/L(25 ºC) |
| Merck | 14,3704 |
| CAS DataBase Reference | 57-91-0(CAS DataBase Reference) |
| NIST Chemistry Reference | Estra-1,3,5(10)-triene-3,17alpha-diol(57-91-0) |
| EPA Substance Registry System | Estra-1,3,5(10)-triene-3,17-diol, (17.alpha.)- (57-91-0) |
Description and Uses
Estradiol (known as α-Estradiol or 17 α-Estradiol) is a biologically active estrogen in human breast cancer cells in tissue culture. 17-Εstradiol and its selective receptor, ER-X, are not part of a classical hormone/receptor endocrine system but of a system with important autocrine/paracrine functions in the developing and adult brain. 17-Estradiol may have enormous implications for hormone replacement strategies at the menopause and in the treatment of such neurodegenerative disorders as Alzheimer’s disease and ischemic stroke.
Safety
| Symbol(GHS) |   GHS08,GHS09 |
| Signal word | Danger |
| Hazard statements | H341-H351-H360F-H362-H410 |
| Precautionary statements | P201-P202-P260-P263-P273-P308+P313 |
| Hazard Codes | T,Xn |
| Risk Statements | 45-48-40 |
| Safety Statements | 53-45-24/25-22 |
| RIDADR | UN 2811 6.1/PG 2 |
| WGK Germany | 3 |
| RTECS | KG3750000 |
| F | 8-10 |
| HS Code | 29372390 |
