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A4011212

Estradiol valerate , ≥98% , 979-32-8

Synonym(s):
β-Estradiol 17-valerate;1,3,5(10)-Estratriene-3,17β-diol 17-pentanote

CAS NO.:979-32-8

Empirical Formula: C23H32O3

Molecular Weight: 356.51

MDL number: MFCD00056541

EINECS: 213-559-2

Pack Size Price Stock Quantity
1G RMB146.40 In Stock
5G RMB532.00 In Stock
25g RMB1936.80 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 144°C
Boiling point: 438.83°C (rough estimate)
Density  1.1024 (rough estimate)
refractive index  1.4700 (estimate)
storage temp.  Sealed in dry,Room Temperature
solubility  Practically insoluble in water, soluble in alcohol.
pka 10.25±0.60(Predicted)
form  Solid
color  White to off-white
Merck  13,3738
BRN  2480357
InChI InChI=1/C23H32O3/c1-3-4-5-22(25)26-21-11-10-20-19-8-6-15-14-16(24)7-9-17(15)18(19)12-13-23(20,21)2/h7,9,14,18-21,24H,3-6,8,10-13H2,1-2H3/t18-,19-,20+,21+,23+/s3
InChIKey RSEPBGGWRJCQGY-RBRWEJTLSA-N
SMILES C[C@]12CC[C@]3([H])C4C=CC(O)=CC=4CC[C@@]3([H])[C@]1([H])CC[C@@H]2OC(=O)CCCC |&1:1,4,15,17,21,r|
CAS DataBase Reference 979-32-8(CAS DataBase Reference)

Description and Uses

Estradiol valerate (EV), sold for use by mouth under the brand name Progynova and for use by injection under the brand names Delestrogen and Progynon Depot among others, is an estrogen medication. In women, it is used in hormone therapy for menopausal symptoms and low estrogen levels, hormone therapy for transgender women, and in hormonal birth control. It is also used in the treatment of prostate cancer in men. The medication is taken by mouth or by injection into muscle or fat once every 1 to 4 weeks.

Estradiol valerate is a female hormone (estrogen). It is used to reduce symptoms of menopause which are vaginal dryness, hot flashes, and others. The symptoms of menopause manifest because the body is making less estrogen; with estradiol valerate, these symptoms are brought to the lowest minimum. This medication therapy can also produce enough estrogen in women with ovarian failure, hypogonadism and can be used by men to treat prostate cancer (palliation only).

Safety

Symbol(GHS) 
GHS08,GHS09
Signal word  Warning
Hazard statements  H351-H361fd-H362-H410
Precautionary statements  P202-P260-P263-P264-P273-P308+P313
Hazard Codes  T
Risk Statements  60-61
Safety Statements  53-45
WGK Germany  3
RTECS  KG5793000
HS Code  29372390

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