Tryptophol , 97%(GC) , 526-55-6

Synonym(s):
2-(3-Indolyl)ethanol;3-Indoleethanol;IEA;NSC 3884;Tryptophol

CAS NO.：526-55-6

Empirical Formula: C10H11NO

Molecular Weight: 161.2

MDL number: MFCD00005659

EINECS: 208-393-2

PRODUCT Properties

• Melting point: 56-59 °C(lit.)
• Boiling point: 174 °C (2.02527 mmHg)
• Density: 1.0840 (rough estimate)
• refractive index: 1.5200 (estimate)
• Flash point: 255 °C
• storage temp.: Keep in dark place,Sealed in dry,Room Temperature
• solubility: methanol: 0.1 g/mL, clear
• pka: 15.16±0.10(Predicted)
• form: Crystalline Mass, Crystals, Flakes or Powder
• color: Off-white to brown
• Water Solubility: 10 g/L (20 ºC)
• Merck: 14,9798
• BRN: 125553
• InChIKey: MBBOMCVGYCRMEA-UHFFFAOYSA-N
• LogP: 1.280 (est)
• CAS DataBase Reference: 526-55-6(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-indole-3-ethanol(526-55-6)
• EPA Substance Registry System: 1H-Indole-3-ethanol (526-55-6)

Description and Uses

Reactant for preparation of:

• Inhibitors of the C-terminal domain of RNA polymerase II and their antitumor activities
• Anti-HIV-1 agents
• Inhibitors of Protein-Protein Interactions
• Partial agonists of the serotonin 5-HT1A receptor
• Growth hormone secretagogues
• Vascular endothelial growth factor (VEGF) inhibitors
• A2B adenosine receptor ligands
• Potential detoxification inhibitors of the crucifer phytoalexin brassinin
• Inhibitors of interleukine 6
• Dual binding site acetylcholinesterase inhibitors

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H315-H319-H335
• Precautionary statements: P261-P271-P280
• Hazard Codes: Xi
• Safety Statements: 24/25
• WGK Germany: 3
• RTECS: KL3685000
• F: 8
• Hazard Note: Irritant
• TSCA: Yes
• HS Code: 29339990
• Toxicity: LD50 intraperitoneal in mouse: 351mg/kg