Hemin , 10mMinDMSO , 16009-13-5

Synonym(s):
Chloro(protoporphyrinato)iron(III);Chlorohemin;Chloroprotoporphyrin IX iron(III);Ferriprotoporphyrin IX chloride;Hemin(chloride)

CAS NO.：16009-13-5

Empirical Formula: C34H31ClFeN4O4-

Molecular Weight: 650.94

MDL number: MFCD00010726

EINECS: 240-140-1

PRODUCT Properties

• Melting point: 300 °C
• storage temp.: 2-8°C
• solubility: 1.4 M NaOH: soluble25mg/mL
• form: crystal
• color: black
• Water Solubility: practically insoluble
• Merck: 14,4644
• BRN: 5229914
• Exposure limits: ACGIH: TWA 1 mg/m3; NIOSH: TWA 1 mg/m3
• Stability: Stable. Incompatible with strong oxidizing agents. Combustible.
• InChIKey: BTIJJDXEELBZFS-HXFTUNQESA-K
• SMILES: [Cl-][Fe+3]123[N-]4C5C(C)=C(C=C)C4=CC4C(C)=C(C=C)C(=CC6=C(C)C(CCC(=O)[O-])=C(C=C7C(CCC(=O)[O-])=C(C)C(C=5)=N17)[N-]26)N3=4.[H+]

Description and Uses

Hemin is a metalloporphyrin compound with a relatively simple structure. It is formed by the complexation of a molecule of ferrous iron and protoporphyrin. It is an in vitro group substitute of natural heme and its chemical properties are similar to that of heme. Heme, an essential small molecule in living organisms, can be found abundantly in various organisms including animals, plants, microorganisms, and algae.

Hemin is used in cellular protection and control mechanism. It stimulates the synthesis of globulin. It is also used to study the bacterial strains and growth conditions, in the short-term colony assays and cell transfections. Further, it is used to treat the symptoms of various porphyrias. In addition, it is used in the preparation of agar medium for the bacteria culture.

Safety

• Symbol(GHS): GHS08
• Signal word: Warning
• Hazard statements: H334
• Precautionary statements: P261-P285-P304+P341-P342+P311-P403-P501c
• Hazard Codes: Xi
• Risk Statements: 36/37/38
• Safety Statements: 24/25-22-36-26
• WGK Germany: 3
• RTECS: LJ8080000
• F: 8
• TSCA: Yes
• HS Code: 29349990