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A7665058

PenicillinGpotassiumsalt , 10mMinDMSO , 113-98-4

Synonym(s):
Benzylpenicillin potassium salt;Penicillin G potassium salt

CAS NO.:113-98-4

Empirical Formula: C16H17KN2O4S

Molecular Weight: 372.48

MDL number: MFCD00036193

EINECS: 204-038-0

Pack Size Price Stock Quantity
1ml RMB159.20 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 214-217 C
alpha  D22 +285° (c = 0.748 in water)
refractive index  294 ° (C=1, H2O)
storage temp.  Sealed in dry,Store in freezer, under -20°C
solubility  H2O: 100 mg/mL
form  powder
color  Needles from butanol (aq)
PH pH (10g/L, 25℃) : 5.0~7.5
Water Solubility  Soluble in water (100 mg/ml), methanol, ethanol (sparingly), and alcohol. Insoluble in chloroform.
Merck  14,7094
BRN  3832841
Stability: Hygroscopic
InChIKey IYNDLOXRXUOGIU-LQDWTQKMSA-M
SMILES N12C([C@@H](NC(=O)CC3=CC=CC=C3)[C@@]1([H])SC(C)(C)[C@@H]2C([O-])=O)=O.[K+] |&1:2,13,19,r|

Description and Uses

Benzylpenicillin potassiumwas the first crystalline penicillin produced on an industrial scale , . It is produced in the pure state by the addition of phenylacetate to a culture of Penicillium chrysogenum. The crystalline benzylpenicillin potassium contains 1598 U/mg.

Penicillin G is a narrow spectrum antibiotic derived from Streptococcus pneumoniae. Penicillin G potassium salt is used as a cell culture additive as an antibiotics. Use to inhibit the synthesis of bacterial cell walls by inhibition of the cell wall peptidoglycan chain cross-lining. It is the drug of choice for groups A, B, C and G streptococci, nonenterococcal group D streptococci, viridians group streptococci, and non-penicillinase producing staphylococcus. The potassium salt has been used to study murosomes of staphylococci and the penicillin-induced lysis of Streptococcus mutans.

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H317
Precautionary statements  P261-P272-P280-P302+P352-P333+P313-P362+P364
Hazard Codes  Xn,C,F
Risk Statements  42/43-34-11
Safety Statements  36/37-45-36/37/39-26-16-60-37-24-22
WGK Germany  2
RTECS  XH9700000
10-23
TSCA  Yes
HS Code  29411000
Toxicity LD50 oral in rabbit: 5848mg/kg

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