PenicillinGpotassiumsalt , 10mMinDMSO , 113-98-4
Synonym(s):
Benzylpenicillin potassium salt;Penicillin G potassium salt
CAS NO.：113-98-4
Empirical Formula: C16H17KN2O4S
Molecular Weight: 372.48
MDL number: MFCD00036193
EINECS: 204-038-0
| Pack Size | Price | Stock | Quantity |
| 1ml | RMB159.20 | In Stock |
|
| others | Enquire |
PRODUCT Properties
| Melting point: | 214-217 C |
| alpha | D22 +285° (c = 0.748 in water) |
| refractive index | 294 ° (C=1, H2O) |
| storage temp. | Sealed in dry,Store in freezer, under -20°C |
| solubility | H2O: 100 mg/mL |
| form | powder |
| color | Needles from butanol (aq) |
| PH | pH (10g/L, 25℃) : 5.0～7.5 |
| Water Solubility | Soluble in water (100 mg/ml), methanol, ethanol (sparingly), and alcohol. Insoluble in chloroform. |
| Merck | 14,7094 |
| BRN | 3832841 |
| Stability: | Hygroscopic |
| InChIKey | IYNDLOXRXUOGIU-LQDWTQKMSA-M |
| SMILES | N12C([C@@H](NC(=O)CC3=CC=CC=C3)[C@@]1([H])SC(C)(C)[C@@H]2C([O-])=O)=O.[K+] |&1:2,13,19,r| |
Description and Uses
Benzylpenicillin potassiumwas the first crystalline penicillin produced on an industrial scale , . It is produced in the pure state by the addition of phenylacetate to a culture of Penicillium chrysogenum. The crystalline benzylpenicillin potassium contains 1598 U/mg.
Penicillin G is a narrow spectrum antibiotic derived from Streptococcus pneumoniae. Penicillin G potassium salt is used as a cell culture additive as an antibiotics. Use to inhibit the synthesis of bacterial cell walls by inhibition of the cell wall peptidoglycan chain cross-lining. It is the drug of choice for groups A, B, C and G streptococci, nonenterococcal group D streptococci, viridians group streptococci, and non-penicillinase producing staphylococcus. The potassium salt has been used to study murosomes of staphylococci and the penicillin-induced lysis of Streptococcus mutans.
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H317 |
| Precautionary statements | P261-P272-P280-P302+P352-P333+P313-P362+P364 |
| Hazard Codes | Xn,C,F |
| Risk Statements | 42/43-34-11 |
| Safety Statements | 36/37-45-36/37/39-26-16-60-37-24-22 |
| WGK Germany | 2 |
| RTECS | XH9700000 |
| F | 10-23 |
| TSCA | Yes |
| HS Code | 29411000 |
| Toxicity | LD50 oral in rabbit: 5848mg/kg |
