PenicillinGsodiumsalt , USP level , 69-57-8

Synonym(s):
Benzylpenicillin sodium salt;Penicillin G sodium salt

CAS NO.：69-57-8

Empirical Formula: C16H17N2NaO4S

Molecular Weight: 356.37

MDL number: MFCD00069666

EINECS: 200-710-2

PRODUCT Properties

• Melting point: 209-212°C
• alpha: D24.8 +301° (c = 2.0 in water)
• Density: 1.41
• refractive index: 300 ° (C=2, H2O)
• storage temp.: Inert atmosphere,2-8°C
• solubility: H₂O: 100 mg/mL Solutions should be filter sterilized and stored at 2-8°C for 1 week or at -20°C for extended periods. Solutions are stable at 37°C for 3 days.
• form: powder
• color: colorless or white
• PH: 5.5-7.5 (3% in H2O)
• Water Solubility: 5-10 g/100 mL at 25 ºC
• Merck: 14,7094
• BRN: 3834217
• Stability: Stability Stable, but incompatible with a wide variety of materials, including acids, oxidizing agents, heavy metals, alcohols, glycerol, thiomersal, many surface-active agents, alkalies, peroxides, reducing agents, lanolin, glycol, sugars, amines, iodine, iodides, thiols. Hygroscopic.
• CAS DataBase Reference: 69-57-8(CAS DataBase Reference)
• EPA Substance Registry System: Penicillin G sodium (69-57-8)

Description and Uses

Penicillin G is a narrow spectrum natural antibiotic. It is effective against Streptococcus pneumoniae, groups A, B, C and G streptococci, nonenterococcal group D streptococci, viridans group streptococci, and non-penicillinase producing staphylococcus. It has been used to study the diagnostic and therapeutic implications of gentamicin-resistant Enterococcus faecalis sequence type 6 with reduced penicillin susceptibility and in cell culture both alone and combined with streptomycin and other antibiotics.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H317
• Precautionary statements: P261-P272-P280-P302+P352-P333+P313-P362+P364
• Hazard Codes: Xn,Xi
• Risk Statements: 42/43
• Safety Statements: 22-36/37-45
• WGK Germany: 2
• RTECS: XH9800000
• F: 10-23
• HS Code: 29411000
• Toxicity: LD50 oral in rat: 6916mg/kg