Ipriflavone , 10mMinDMSO , 35212-22-7

Synonym(s):
7-Isopropoxy-3-phenyl-4H-1-benzopyran-4-one;Ipriflavone

CAS NO.：35212-22-7

Empirical Formula: C18H16O3

Molecular Weight: 280.32

MDL number: MFCD00221719

EINECS: 609-092-2

PRODUCT Properties

• Melting point: 116-120 °C(lit.)
• Boiling point: 363.04°C (rough estimate)
• Density: 1.2170 (rough estimate)
• refractive index: 1.4700 (estimate)
• storage temp.: Sealed in dry,Room Temperature
• solubility: DMF:20.0(Max Conc. mg/mL);71.35(Max Conc. mM); DMF:PBS (pH 7.2) (1:4):0.2(Max Conc. mg/mL);0.71(Max Conc. mM); DMSO:33.11(Max Conc. mg/mL);118.11(Max Conc. mM); Ethanol:1.5(Max Conc. mg/mL);5.35(Max Conc. mM)
• form: powder to crystal
• color: White to Almost white
• Merck: 14,5074
• InChI: InChI=1S/C18H16O3/c1-12(2)21-14-8-9-15-17(10-14)20-11-16(18(15)19)13-6-4-3-5-7-13/h3-12H,1-2H3
• InChIKey: SFBODOKJTYAUCM-UHFFFAOYSA-N
• SMILES: C1OC2=CC(OC(C)C)=CC=C2C(=O)C=1C1=CC=CC=C1
• LogP: 4.245 (est)

Description and Uses

Ipriflavone, a derivative of isoflavone, is a calcium metabolism regulator useful in the treatment of primary and secondary osteoporosis, as well as disorders of osteogenesis. It appears to be without significant side-effects.

7-Isopropoxy-3-phenyl-4H-1-benzopyran-4-one (Ipriflavone) has been used as a model drug in a study to functionalize the mesoporous bioactive glasses (MBG). Study suggested that since ipriflavone is a hydrophobic anti-osteoporotic drug, it easily attaches to the surface of MBG and results in long-term drug delivery.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H315-H319-H335
• Precautionary statements: P261-P305+P351+P338
• Hazard Codes: Xi
• Risk Statements: 36/37/38
• Safety Statements: 24/25-36/37/39-27-26
• WGK Germany: 2
• RTECS: DJ3100500
• HS Code: 29329990