Home Categories API 3β-Hydroxy-Δ5-cholenicAcid
A7581558

3β-Hydroxy-Δ5-cholenicAcid , 10mMinDMSO , 5255-17-4

Synonym(s):
3β-Hydroxy-5-cholen-24-oic acid

CAS NO.:5255-17-4

Empirical Formula: C24H38O3

Molecular Weight: 374.57

MDL number: MFCD00069468

Pack Size Price Stock Quantity
1ml RMB159.20 In Stock
others     Enquire
Update time: 2022-07-08

PRODUCT Properties

Melting point: 232°C
Boiling point: 522.8±23.0 °C(Predicted)
Density  1.11±0.1 g/cm3(Predicted)
refractive index  -39.5 ° (C=1, Dioxane)
storage temp.  Refrigerator
solubility  Dioxane (Slightly, Sonicated), DMF (Slightly), DMSO (Slightly, Heated, Sonicated)
form  Solid
pka 4.76±0.10(Predicted)
color  White to Pale Yellow

Description and Uses

Cholenic acid is a monohydroxy bile acid. It is a cholesterol oxidation product formed by 7α-hydroxylation of 27-hydroxycholesterol (Item Nos. 14790 | 14791), as well as a precursor in the biosynthesis of chenodeoxycholic acid . Levels of cholenic acid are increased in patients with neonatal liver disease harboring mutations in CYP7A1, the gene encoding 7α-hydroxylase, as well as in patients with intrahepatic and extrahepatic cholestasis.

5-Cholenic Acid-3β-ol is a bile acid of which the metabolism in humans results in the primary bile acids lithocholic acid and chenodeoxycholic. It is found in hgher concentrations in meconium of premature human babies when compared to full term babies.

Safety

Safety Statements  22-24/25
WGK Germany  3

RELATED PRODUCTS