Home Categories Biochemical Engineering Se-(Methyl)seleno-<small>L</small>-cysteine
A7439012

Se-(Methyl)seleno-<small>L</small>-cysteine , >98.0%(HPLC)(T) , 26046-90-2

CAS NO.:26046-90-2

Empirical Formula: C4H9NO2Se

Molecular Weight: 182.08

MDL number: MFCD00800565

Pack Size Price Stock Quantity
10MG RMB125.60 In Stock
50mg RMB347.20 In Stock
100MG RMB605.60 In Stock
250mg RMB1194.40 In Stock
1g RMB3679.20 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 177 °C(dec.)
Boiling point: 314.1±37.0 °C(Predicted)
storage temp.  Keep in dark place,Inert atmosphere,2-8°C
solubility  DMSO (Slightly), Water (Slightly)
pka 2.17±0.10(Predicted)
form  Powder
color  White to slightly yellow
InChI InChI=1S/C4H9NO2Se/c1-8-2-3(5)4(6)7/h3H,2,5H2,1H3,(H,6,7)/t3-/m0/s1
InChIKey XDSSPSLGNGIIHP-VKHMYHEASA-N
SMILES C(O)(=O)[C@H](C[Se]C)N
LogP -0.043 (est)

Description and Uses

Se-methyl selenocysteine (MSC) is a naturally occurring selenium compoundwith favourable pharmacokinetic properties andth high peroral bioavailability in humans. MSC is synthesized by plants such as garlic, astragalus, onions and broccoli. Se-methylselenocysteine has been proven to have a chemo-preventive property, which is shown by several authors via various cell culture models and animal models. It has also been shown to have anti-carcinogenic properties by inducing cell cycle arrest and apoptotic cell death. It is considered a pro-drug because the compound per se is not toxic unless it is metabolized by the enzymes Kynurenine aminotransferase 1 (KYAT1), Kynurenine aminotransferase 3 (KYAT3) and cystathionine γ-lyase (CTH). Of these, KYAT1 plays a vital role in MSC metabolism.

2-Amino-3-methylselenyl propionic acid is an inhibitor of DMBA-induced mammary tumors.

Safety

Symbol(GHS) 
GHS06,GHS08,GHS09
Signal word  Danger
Hazard statements  H301+H331-H373-H410
Precautionary statements  P501-P273-P260-P270-P271-P264-P391-P314-P301+P310+P330-P304+P340+P311-P403+P233-P405
Hazard Codes  T,N
Risk Statements  23/25-33-50/53
Safety Statements  20/21-28-45-60-61-28A
RIDADR  UN 3283 6.1/PG 2
WGK Germany  3
10-23
HS Code  29319090

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