Sulfamethazine , Analysis standard , 57-68-1

Synonym(s):
4,6-Dimethylsulfadiazine;4-Amino-N-(4,6-dimethyl-2-pyrimidinyl)benzenesulfonamide;Sulfadimethyldiazine;Sulfadimidine;Sulfamethazine

CAS NO.：57-68-1

Empirical Formula: C12H14N4O2S

Molecular Weight: 278.33

MDL number: MFCD00006066

EINECS: 200-346-4

Pack Size	Price	Stock	Quantity
250MG	RMB295.20	In Stock
others			Enquire

Update time: 2022-07-08

PRODUCT Properties

Melting point:	197 °C
Boiling point:	294°C (rough estimate)
Density	1.2997 (rough estimate)
refractive index	1.6440 (estimate)
storage temp.	2-8°C
solubility	acetone: soluble50mg/mL
form	Crystalline Powder
pka	7.4, 2.65(at 25℃)
color	white to off-white
Water Solubility	150mg/100mL (29 ºC)
Merck	14,8905
BRN	261304
Stability:	Stable, but light sensitive. Incompatible with strong oxidizing agents.
CAS DataBase Reference	57-68-1(CAS DataBase Reference)
IARC	3 (Vol. 79) 2001
NIST Chemistry Reference	Sulfamethazine(57-68-1)
EPA Substance Registry System	Sulfamethazine (57-68-1)

Description and Uses

Sulfamethazine is an antibacterial sulfonamide. Like other sulfonamides, sulfamethazine is bacteriostatic, competitively inhibiting dihydropteroate synthase to block folate synthesis and inhibit growth and multiplication. Sulfamethazine is metabolized by cytochrome P450 isoforms and arylamine N-acetyltransferase 2 in a sex-dependent manner.

Sulfamethazine is an antibacterial.This compound is a contaminant of emerging concern (CECs).

Safety

Symbol(GHS)	GHS08
Signal word	Danger
Hazard statements	H362-H315-H334-H317-H319
Precautionary statements	P264-P280-P302+P352-P321-P332+P313-P362-P261-P272-P280-P302+P352-P333+P313-P321-P363-P501-P264-P280-P305+P351+P338-P337+P313P-P201-P260-P263-P264-P270-P308+P313-P261-P285-P304+P341-P342+P311-P501
Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	23-24/25-36-26
WGK Germany	2
RTECS	WO9275000
F	10
TSCA	Yes
HS Code	29350090
Hazardous Substances Data	57-68-1(Hazardous Substances Data)
Toxicity	LD50 i.p. in mice: 1.06 g/kg (Bobranski)