Home Categories Chemical Reagents Sodium bis(trimethylsilyl)amide
A7288012

Sodium bis(trimethylsilyl)amide , 2.0MinTHF(40%) , 1070-89-9

Synonym(s):
Hexamethyldisilazane sodium salt;Hexamethyldisilazane sodium salt solution;HMN-Na Sol;NaHMDS solution

CAS NO.:1070-89-9

Empirical Formula: C6H18NNaSi2

Molecular Weight: 183.37

MDL number: MFCD00009835

EINECS: 213-983-8

Pack Size Price Stock Quantity
100ML RMB194.40 In Stock
500ML RMB523.20 In Stock
800ml RMB719.20 In Stock
1L RMB827.20 In Stock
5L RMB3999.20 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 171-175 °C (lit.)
Boiling point: 67°C
Density  0.904 g/mL at 25 °C
Flash point: 43 °F
storage temp.  2-8°C
solubility  Soluble in hexane, toluene, ether,terahydrofuran, benzene and toluene.
form  Liquid
Specific Gravity 0.9
color  Clear orange to brown
Water Solubility  reacts
Sensitive  Moisture Sensitive
Hydrolytic Sensitivity 8: reacts rapidly with moisture, water, protic solvents
BRN  3629917
Exposure limits ACGIH: TWA 50 ppm; STEL 100 ppm (Skin)
OSHA: TWA 200 ppm(590 mg/m3)
NIOSH: IDLH 2000 ppm; TWA 200 ppm(590 mg/m3); STEL 250 ppm(735 mg/m3)

Description and Uses

Sodium bis(trimethylsilyl)amide is a synthetically useful reagent in that it combines both high basicity and nucleophilicity, each of which may be exploited for useful organic transformations such as selective formation of enolates, preparation of Wittig reagents, formation of acyl anion equivalents, and the generation of carbenoid species. As a nucleophile, it has been used as a nitrogen source for the preparation of primary amines.It is useful as a sterically hindered base and as a nucleophile.

Safety

Symbol(GHS) 
GHS05
Signal word  Danger
Hazard statements  H314
Precautionary statements  P260-P280-P303+P361+P353-P304+P340+P310-P305+P351+P338-P363
Hazard Codes  C,F
Risk Statements  14-34-19-11-67-65-63-48/20-14/15-40-37
Safety Statements  26-45-62-36/37/39-33-16-43-8
RIDADR  UN 3263 8/PG 2
WGK Germany  3
10-21
TSCA  Yes
HazardClass  4.3
PackingGroup  III
HS Code  29319090

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